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In this book it will be possible to immerse the concept of depression from its connection with diseases such as Parkinson's, Diabetes and Sclerosis. Is there really depression when we talk about neurodegenerative or systemic diseases? In these pages the reader will find not only a small disclosure about these diseases but a gnoseological, logical and ontological analysis of what depression can be in order to discern what relationship there may be between physical and emotional symptoms. If you are one of those who prefer more questions beyond any topic, this is your book