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This book will compile a collection of chapters dedicated to varied aspects of PPPM in neuropsychiatric and neurodegenerative diseases. Among the topics to be covered are:§Recent advances in ALS research§News about Clinical aspects and advanced therapy approaches in personalized treatment of ALS Schizophrenia: New treatments and clinical aspects§Predictive, Preventive and Personalised Medicine in aging macular degeneration§Advances in Multiple Sclerosis Pharmacogenetics, Tailoring Treatment Efficacy, Safety and Regimen Selection§Multiple sclerosis related biomarkers: perspectives for clinical application§Preventive clinical trials in brain aging: new trends & the need of guidelines§MCI_ clinical guidelines in early diagnosis of dementia§Alzheimer's disease: diagnostics, prognostics and the road to prevention§Biomarkers for early diagnosis of Parkinson's and Alzheimer's diseases§Synucleinopathies, tauopathies, TDP-43 proteinopathies and amyloidosis PSP, MSA and other parkinsonisms§