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Heart failure research is a most active area of research in academic, industrial and government-sponsored research and receives intense clinical attention. The recent recognition that inflammation is a risk factor and prognostic factor for heart disease has laid ground for preventive medicine and even anti-infective strategies in prevention and treatment of heart failure. §Provides a new perspective on the etiology of cardiac failure§Covers the latest developments§Discusses future treatments for heart failure§Ideal for researchers and clinicians§