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The proceedings of this symposium focus on the new and exciting fluoroquinolone moxifloxacin. Physicians and scientists from around the world have contributed to this effort, and the information in these proceedings has been organized as follows:§Part I: Antimicrobial Chemotherapy Part II: Preclinical Microbiology§Part III: Pharmacology§Part IV: Clinical Needs in the Millenium§Part V: Round Table Discussion§It is hoped that the reader will gain an appreciation of the various basic and clinical issues pertaining to the fluoroquinolones in general and moxifloxacin in particular and the role of this agent in the management of respiratory tract infections.