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This book investigates the functioning and ecosystem of biorefineries and assesses the potential of the industrial bioeconomy. The authors present a case study of the biorefinery of Bazancourt Pomacle, near Reims, France, as a top-notch illustration of the creation, work processes, financing, provision of environmental services, competitive benefits and future prospects of a bioeconomy. Analysing the case of Bazancourt Pomacle, the authors show the wide range of products produced by the integrated biorefinery such as food, bioenergy, molecules for cosmetrics and nutrients going back to the farms. They also analyse Bazancourt Pomacle as an open innovation platform which encompasses several layers of R&D, including three industrial Chairs from leading engineering and business schools in France. Illustrating a number of world famous success stories actually started in Bazancourt Pomacle, the authors also investigate the provision of pilot and demonstration plants as inescapable steps in the scaling up process from the lab to the industrial capacity. The book provides a systematic overview about lessons learned and data on an industrial bioeconomy. Investors, decision makers, public policy shapers, analysts and scholars will learn about history, actors, economics, industrial symbiosis, role of cooperatives, R&D, future prospects of a top-notch biorefinery and bio-based cluster in Europe.