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This volume highlights proteomics studies§of quantitative PTM changes in both peripheral and central nervous system§proteomes utilizing the most recent advances in mass spectrometry. Chapters§include practical information pertaining to the fundamentals of sample§preparation, liquid chromatography, and tandem mass spectrometry instrumental§analysis and will elucidate best practices in the interpretation of data using§modern bioinformatics approaches. Written for the popular Neuromethods series,§chapters include the kind of detail and key implementation advice that ensures§successful results in the laboratory.§§Authoritative§and practical, Analysis of Post-Translational Modifications and§Proteolysis in Neuroscience aims to ensure successful results§in the further study of this vital field.§