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Azapropazone

20 years of clinical use

Language EnglishEnglish
Book Paperback
Book Azapropazone K. D. Rainsford
Libristo code: 02191061
Publishers Springer, September 2011
Azapropazone is a chemically unique non-steroidal anti-inflammatory drug (benzotriazine oxide) which... Full description
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Azapropazone is a chemically unique non-steroidal anti-inflammatory drug (benzotriazine oxide) which has found successful clinical applications in the therapy of a wide variety of arthritic conditions. This book summarizes the progress and critically reviews the clinical use and experimental studies since its introduction 20 years ago. Several studies focus on the physiochemical, pharmacological and toxico logical properties of this drug. The studies suggest that it has some unique properties compared with other non-steroidal anti-inflammatory drugs. Among these the novel observations are that azapropazone inhibits several non-prostaglandin-related leucocyte functions, especially superoxide anion production. These serve as a basis for investigations which are reviewed showing the potential for the drug to prevent the pathological consequencies of myocardial ischaemia. The preparation of this book would not have been possible without the cooperation of the four companies who produce, market, or have research involvement with azapropazone, namely Siegfried AG (the manufacturers of the drug), A.H. Robins (U.K.) Co. Ltd., Robapharm AG (Switzerland) and E.!. duPont de Nemours (U.S.A., Switzerland and F.R.G.).

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About the book

Full name Azapropazone
Language English
Binding Book - Paperback
Date of issue 2011
Number of pages 256
EAN 9789401068062
ISBN 9401068062
Libristo code 02191061
Publishers Springer
Weight 480
Dimensions 155 x 235 x 17
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