Systemic Lupus Erythematosus

Systemic Lupus Erythematosus: Basic, Applied and Clinical Aspects has been an essential resource for scientists and clinicians in this field since its original publication in 2015. The third edition of this work has been completely updated and expanded with the latest scientific and clinical developments in Systemic Lupus Erythematosus (SLE) to date. Contributors at the forefront of each topic come together to enhance content on epidemiology and diagnosis, pathogenesis, mechanisms of tissue damage, clinical aspects of the disease, antiphospholipid syndrome, and treatments. Also added is the latest information on new treatments, criteria, monogenic forms of lupus, insights on the role of microbiome, and advances in understanding disease pathogenesis. This must-have reference is an indispensable resource for specialists in the diagnosis and management of patients with SLE as well as early career or experienced investigators studying basic aspects of the disease. It is a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a key reference work for hospital libraries. - Provides the very latest overview of the pathogenesis of systemic lupus erythematosus- Distills current understanding of the cellular, molecular, genetic, and environmental factors that instigate and drive the disease- Includes comprehensive coverage of clinical features, including fatigue, organ system manifestations, overlap syndromes, infections, and more- Conveys the very latest understanding of mechanisms of tissue damage, including immune complexes, antibodies, and other mechanisms that lead to organ damage- Discusses the latest treatment options on disease modifying or disease controlling agents