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Dose Finding by the Continual Reassessment Method

Language EnglishEnglish
E-book Adobe ePub DRM
Publishers Chapman and Hall/CRC, March 2011
This book presents the continual reassessment method (CRM) as a tool for dose-finding studies. With... Full description
? points 606 b
90 923 Ft
In stock Immediate digital delivery

This book presents the continual reassessment method (CRM) as a tool for dose-finding studies. With a focus on the implementation and practice of the CRM and its variations, it explains how the CRM may be calibrated and extended to suit common clinical settings. The book includes examples of real clinical trials data to illustrate the calibration techniques and shows how R can be used to carry out the techniques. It reviews the literature, related methodology, and theoretical properties of the CRM. It also explores alternatives for situations where the CRM fails.

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