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The Amulet Gene
Assessment of Genetics Mutations in RNF213, ACTA2, GUCY1A3 Genes induction Moyamoya disease
English
165 b
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Today, neurological diseases are one of the most important factor which causes death. Including the deadly nerve disorders, neurological diseases can be noted Moyamoya disease. This disease X-linked recessive inheritance pattern is transferred to the next generation. The disease is caused by mutations in genes in nerve cells. But epigenetic factors also have an important role in the ability to induce the disease. In this study we have analyzed 50 people. 20 patients Moyamoya disease and 30 persons control group. The genes RNF213 on chromosome 17q25, ACTA2 on chromosome 10q23.3, GUCY1A3 on chromosome 4q32, were analyzed in terms of genetic mutations. In this study, people who have genetic mutations were targeted, with nervous disorders, Moyamoya disease. In fact, all of people with Moyamoya disease. 20 patients Moyamoya disease had a genetic mutations in the genes RNF213 on chromosome 17q25, ACTA2 on chromosome 10q23.3, GUCY1A3 on chromosome 4q32 Moyamoya disease. Any genetic mutations in the target genes control group, were not show. This is Amulet Gene.
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