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In this textbook the brief outline on osteoradionecrosis has been focused, in which the etiology, incidence and prevalence, risk factors, pathophysiology, prevention, treatment, advancements in osteoradionecrosis has been discussed. Highlights on the hyperbaric oxygen therapy has been put forth. By going through this book, reader will know the brief idea about the ill effects of the radiotherapy which indeed will help in preventing osteoradionecrosis.