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on-chip Biosensorik

Charakterisierung eines Fluidik-Chip-Systems zurDetektion von antioxidativ wirksamen Substanzen im organisch-wässrigen Medium

Language GermanGerman
Book Paperback
Book on-chip Biosensorik Robert Sczech
Libristo code: 06818061
Publishers VDM Verlag Dr. Müller, November 2007
In dieser Abhandlung wurde einFluidik-Chip-System für die Charakterisierung vonAntioxidantien im Ein... Full description
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17 783 Ft
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In dieser Abhandlung wurde einFluidik-Chip-System für die Charakterisierung vonAntioxidantien im Einsatz mit organisch-wässrigemMedium untersucht.Es konnte ermittelt werden, bei welchen optimalenParametern im Fließsystem im 30%-igenDMSO/Puffergemisch die reaktiven Sauerstoff-SpeziesH2O2 und O2- auf einem Chip an Cytochromc-modifizierten Elektroden erfolgreich generiert,detektiert und deren Signale durch in Cremesintegrierte Antioxidantien unterdrückt werdenkonnten.Unter Anwendung der ermittelten optimalen ParameterFließgeschwindigkeit und Substratkonzentration,konnte die simultane Generierung reaktiverSauerstoff-Spezies, deren Detektion und derenSignalunterdrückungen durch Antioxidantien (Aox) anden Chipelektroden im 30%-igen DMSO/Puffererfolgreich gezeigt werden.In einem zusätzlichen Schritt wurden Antioxidantieneiner Cremegrundlage hinzugesetzt. Die simultaneSignalunterdrückung der on-chip generierten Signalebeider reaktiven Sauerstoffspezies (ROS) konnte auchunter Verwendung von organisch-wässrigemLösungsmittelgemisch prinzipiell erfolgreichdemonstriert werden.

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About the book

Full name on-chip Biosensorik
Author Robert Sczech
Language German
Binding Book - Paperback
Date of issue 2008
Number of pages 68
EAN 9783639089455
Libristo code 06818061
Publishers VDM Verlag Dr. Müller
Weight 118
Dimensions 150 x 220 x 4

Categories

Mathematics & Science > Biology, life sciences
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