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Nuclear Factor B

Name: Nuclear Factor B
Brand: Springer
SKU: 02184486
Price: 41474 HUF
Availability: InStock
Author: R. Beyaert
ISBN: 9789401039833

Regulation and Role in Disease

R. Beyaert

Language

English

Book Paperback

Libristo code: 02184486

Publishers Springer, November 2012

The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a p... Full description

Libristo code: 02184486

285 b

41 474 Ft

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The transcription factor NF-kappaB and the signaling pathways regulating its activity constitute a paradigm of membrane to nucleus communication. NF-kappaB is central to a number of cellular functions including cell proliferation, apoptosis, and cellular differentiation. This transcription factor also plays essential roles in innate and acquired immunity, and its deregulation leads to important human diseases such as inflammation and cancer. Therefore NF-kappaB, together with the signaling pathways leading to its activation, constitute an attractive therapeutic target. §This book is the first to review and synthesize our knowledge on this interesting transcription factor. It will be of great interest for those entering or already actively working in the NF-kappaB field, as well as a valuable reference for students, established researchers, or clinicians with wider interests in the fields of molecular cell biology and biomedicine.