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Molecular Dynamic Simulation Studies

Language EnglishEnglish
Book Paperback
Book Molecular Dynamic Simulation Studies Vijay Raj Bollapalli
Libristo code: 16123219
Publishers SPS, March 2017
Mdm2 has been identified as a p53 interacting protein towards represses p53 transcriptional activity... Full description
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Mdm2 has been identified as a p53 interacting protein towards represses p53 transcriptional activity.Mdm2 achieves this repression by binding to P53 and blocking the N- terminal transactivation domain of p53. Mdm2 is a p53 responsive gene that is; its transcription can be activated by p53. When p53 is stabilized, the transcription of Mdm2 is also induced, resulting in higher mdm2 protein levels causing recognition and repair, transcription regulation problems leading to cancer. Thus inhibiting the mdm2- p53 interactions has been proven to be most promising approach for cancer therapy.

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About the book

Full name Molecular Dynamic Simulation Studies
Author Vijay Raj Bollapalli, V. Raghavendra Rao Morusupalli
Language English
Binding Book - Paperback
Date of issue 2017
Number of pages 220
EAN 9783330650909
ISBN 3330650907
Libristo code 16123219
Publishers SPS
Weight 344
Dimensions 150 x 220 x 13

Categories

Mathematics & Science > Biology, life sciences > Biochemistry
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