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Molecular Chaperones and Cell Signalling

Name: Molecular Chaperones and Cell Signalling
Brand: Cambridge University Press
SKU: 02024749
Price: 20313 HUF
Availability: InStock
Author: Brian HendersonA. Graham Pockley
ISBN: 9780521177474

Brian HendersonA. Graham Pockley

Language

English

Book Paperback

Libristo code: 02024749

Publishers Cambridge University Press, March 2011

Originally published in 2005, this book reviews understanding of the biological roles of extracellul... Full description

Libristo code: 02024749

135 b

20 313 Ft

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Originally published in 2005, this book reviews understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these proteins are first and foremost protein-folding molecules. Paradigms of protein secretion are reviewed and the evolving concept of proteins (such as molecular chaperones) as multi-functional molecules for which the term 'moonlighting proteins' has been introduced is discussed. The role of exogenous molecular chaperones as cell regulators is examined and the physiological and pathophysiological role that molecular chaperones play is described. In the final section, the potential therapeutic use of molecular chaperones is described and the final chapter asks the question - what does the future hold for the extracellular biology of molecular chaperones?