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Microsatellites: Evolution and Applications

Name: Microsatellites: Evolution and Applications
Brand: Oxford University Press
SKU: 04526842
Price: 47779 HUF
Availability: InStock
Author: David B. Goldstein
ISBN: 9780198504078

David B. Goldstein

Christian Schlotterer

Language

English

Book Paperback

Libristo code: 04526842

Publishers Oxford University Press, June 1999

Microsatellites are short stretches of repeated DNA, found in most genomes, that show exceptional va... Full description

Libristo code: 04526842

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Microsatellites are short stretches of repeated DNA, found in most genomes, that show exceptional variability in humans and most other species. This variability has made microsatellites the genetic marker of choice for most applications, including genetic mapping and studies of the evolutionary connections between species and populations. This book brings together an international group of scientists currently working in microsatellites. Their contributions provide a detailed description of microsatellite biology, focusing on their mutation properties, generation, decay, and possible functional roles. They introduce the theoretical models that underpin the most popular methods for analysing the information that microsatellites can yield, including methods for estimating coalescent times, population divergences, and migration. Finally, the book describes the various ways in which the potential of microsatellites is being harnessed in a range of applications including medical genetics, forensics, genetic mapping, the analysis of human evolution, and conservation genetics.