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Large-Scale High-Resolution Microelectrode Arrays Neurointerfaces

Name: Large-Scale High-Resolution Microelectrode Arrays Neurointerfaces
Brand: Sudwestdeutscher Verlag Fur Hochschulschriften AG
SKU: 06970102
Price: 28095 HUF
Availability: InStock
Author: Kilian Imfeld
ISBN: 9783838104737

System Design and Signal Processing

Kilian Imfeld

Language

German

Book Paperback

Libristo code: 06970102

Publishers Sudwestdeutscher Verlag Fur Hochschulschriften AG, March 2009

Microelectrode arrays (MEAs)-based neuronal§interfaces allow monitoring and stimulating neuronal§net... Full description

Libristo code: 06970102

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Microelectrode arrays (MEAs)-based neuronal§interfaces allow monitoring and stimulating neuronal§networks both in vivo and in vitro. §In vitro methodology is widely used to study and§model at intermediate complexity learning and memory§processes within a large neuronal network. Currently,§commercially available MEA platforms for in vitro§electrophysiology allow concurrent recording from at§most 256 electrodes. However, dissociated neuronal§cultures can consist of up to 100'000 cells within a§monitored area of a few square millimeters. Thus,§substantial spatial subsampling compromises the§continuous observation of a large-scale network down§to the cellular level.§§This book demonstrates a new concept for a system§that can monitor large dissociated neuronal cultures§with 4096 electrodes at high spatial resolutions. The§specific objectives are (i) the design of a complete§large-scale and high-resolution MEA platform and (ii)§the investigation and development of wavelet- and§image-based strategies to manage the large data§streams with respect to real-time neurophysiological§analysis.