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Histone Recognition

Language EnglishEnglish
Book Hardback
Book Histone Recognition Ming-Ming Zhou
Libristo code: 09255758
Publishers Springer International Publishing AG, May 2015
This book provides a timely review of the role of histone modifications in epigenetic control of gen... Full description
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This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.§

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About the book

Full name Histone Recognition
Author Ming-Ming Zhou
Language English
Binding Book - Hardback
Date of issue 2015
Number of pages 282
EAN 9783319181011
ISBN 3319181017
Libristo code 09255758
Publishers Springer International Publishing AG
Weight 720
Dimensions 155 x 235 x 243

Categories

Medicine & Nursing > Medicine: general issues > Medical equipment & techniques > Medical research
Medicine & Nursing > Pre-clinical medicine: basic sciences > Medical genetics
Mathematics & Science > Biology, life sciences > Biochemistry
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