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GPCRs

Structure, Function, and Drug Discovery

Language EnglishEnglish
Book Paperback
Book GPCRs Beata Jastrzebska
Libristo code: 22120894
Publishers Elsevier Books, September 2019
GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveri... Full description
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GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveries and our current understanding of GPCR structure, signaling, physiology, pharmacology and methods of study. In addition to the fundamental aspects of GPCR function and dynamics, international experts discuss crystal structures, GPCR complexes with partner proteins, GPCR allosteric modulation, biased signaling through protein partners, deorphanization of GPCRs, and novel GPCR-targeting ligands that could lead to the development of new therapeutics against human diseases. GPCR association with, and possible therapeutic pathways for, retinal degenerative diseases, Alzheimer’s disease, Parkinson’s disease, cancer and diabetic nephropathy, among other illnesses, are examined in-depth. Addresses our current understanding and novel advances in the GPCR field, directing readers towards recent finding of key significance for translational medicineCombines a thorough discussion of structure and function of GPCRs with disease association and drug discoveryFeatures chapter contributions from international experts in GPCR structure, signaling, physiology and pharmacology

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About the book

Full name GPCRs
Language English
Binding Book - Paperback
Date of issue 2019
Number of pages 500
EAN 9780128162286
ISBN 0128162287
Libristo code 22120894
Publishers Elsevier Books
Weight 1310
Dimensions 216 x 276 x 27
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