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Genotoxic Impurities

Strategies for Identification and Control

Language EnglishEnglish
Book Hardback
Book Genotoxic Impurities Andrew Teasdale
Libristo code: 04883982
Publishers John Wiley & Sons Inc, February 2011
This book examines genotoxic impurities and their impact on the pharmaceutical industry.Specific sec... Full description
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This book examines genotoxic impurities and their impact on the pharmaceutical industry.Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed byasection on safety aspects, including safety tests in vivo and vitro, and data interpretation.The second section addresses the risk posed by genotoxic impurities fromoutside sources and from mutagenswithin DNA.In the final section, the book deals with the quality perspective of genotoxic impurities focused on two critical aspects, the first being the analysis and the second how to practically evaluate the impurities.

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About the book

Full name Genotoxic Impurities
Author Andrew Teasdale
Language English
Binding Book - Hardback
Date of issue 2011
Number of pages 444
EAN 9780470499191
ISBN 0470499192
Libristo code 04883982
Publishers John Wiley & Sons Inc
Weight 804
Dimensions 156 x 243 x 29

Categories

Medicine & Nursing > Pre-clinical medicine: basic sciences > Medical genetics
Medicine & Nursing > Clinical & internal medicine > Diseases & disorders
Medicine & Nursing > Medical specialties, branches of medicine > Pharmacology
Mathematics & Science > Chemistry
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