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Gene Selection Based on Consistency Modelling, Algorithms and Applications - Genetic Algorithm Application in Bioinformatics Data Analysis

Language EnglishEnglish
Book Paperback
Book Gene Selection Based on Consistency Modelling, Algorithms and Applications - Genetic Algorithm Application in Bioinformatics Data Analysis Yingjie Hu
Libristo code: 06810963
Publishers VDM Verlag Dr. Mueller E.K., April 2008
Consistency modeling for gene selection is a new topicemerging from recent cancer bioinformatics res... Full description
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Consistency modeling for gene selection is a new topicemerging from recent cancer bioinformatics research. The result ofclassification or clustering on a training set was often found verydifferent from the same operations on a testing set. Here, theissue is addressed as a consistency problem. In practice, theinconsistency of microarray datasets prevents many typical geneselection methods working properly for cancer diagnosis andprognosis. In an attempt to deal with this problem, a new conceptof performance-based consistency is proposed in this thesis. Theproposed consistency concept has been investigated on eightbenchmark microarray and proteomic datasets. The experimentalresults show that the different microarray datasets have differentconsistency characteristics, and that better consistency can leadto an unbiased and reproducible outcome with good diseaseprediction accuracy.

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About the book

Full name Gene Selection Based on Consistency Modelling, Algorithms and Applications - Genetic Algorithm Application in Bioinformatics Data Analysis
Author Yingjie Hu
Language English
Binding Book - Paperback
Date of issue 2008
Number of pages 112
EAN 9783639008838
ISBN 3639008839
Libristo code 06810963
Weight 159
Dimensions 152 x 229 x 6
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