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Copper Complexes - Vol II

Name: Copper Complexes - Vol II
Brand: LAP Lambert Academic Publishing
SKU: 12628474
Price: 14071 HUF
Availability: InStock
Author: Richa Kothari
ISBN: 9783659880575

Synthesis, Characterization and Biological Evaluation of NNS donor schiff base molecular adducts of Copper (II) Chloride

Richa Kothari

Language

English

Book Paperback

Libristo code: 12628474

Publishers LAP Lambert Academic Publishing, November 2015

NNS Schiff base molecular adducts belong to a group of thiourea derivatives and the biological activ... Full description

Libristo code: 12628474

94 b

14 071 Ft

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NNS Schiff base molecular adducts belong to a group of thiourea derivatives and the biological activities of which are a function of the parent aldehyde or ketone are the most important properties of thiosemicarbazone class of ligands (hydrazine carbothioamindes). Their metal complexes, especially those containing copper (II) and iron (III) are more active than uncoordinated NNS Schiff base molecular adducts and enhanced biological activity of metal thiosemicarbazones has been under investigation for some time. NNS Schiff base molecular adducts are very good ligands and it has been shown that their biological activity is related to their ability to coordinate to metal centres in enzymes. NNS Schiff base molecular adducts are more active in cell destruction, as well as in the inhibition of DNA synthesis. NNS Schiff base molecular adducts are obtained by condensation of thiosemicarbazide or a substituted thiosemicarbazide at the N (4) position with a suitable aldehyde or ketone.