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Calreticulin

Name: Calreticulin
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 02182738
Price: 39822 HUF
Availability: InStock
Author: Marek Michalak
ISBN: 9783662062050

Marek Michalak

Language

English

Book Paperback

Libristo code: 02182738

Publishers Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, April 2013

This book is about calreticulin, a multifunctional calcium binding protein first discovered over 20... Full description

Libristo code: 02182738

271 b

39 822 Ft

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This book is about calreticulin, a multifunctional calcium binding protein first discovered over 20 years ago. The protein has been described in various locations: endoplasmic reticulum, nuclear envelope, cytoplasmic granules, nucleus, cell surface and even secreted into the blood stream. This volume outlines the newly discovered functions for calreticulin including its control of calcium homeostasis, modulation of steroid-sensitive gene expression, control of viral RNA replication, modulation of nuclear transport, role in T lymphocyte activation and cytotoxic killing, chaperone function, control of adhesion-dependent signaling via integrins, possible role in the biology of ticks, in the pathology of autoimmune diseases and in blood function.