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Actin-Binding Proteins and Disease

Language EnglishEnglish
Book Paperback
Book Actin-Binding Proteins and Disease Cris dos Remedios
Libristo code: 01421251
Publishers Springer-Verlag New York Inc., February 2010
There are scattered reports in the published literature citing relationships between actin, actin-bi... Full description
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There are scattered reports in the published literature citing relationships between actin, actin-binding proteins and disease. This volume brings this information together for the first time, with a focus on human disorders. The volume is relevant to a wide readership including cell biologists interested in understanding how structural and functional changes in proteins impact on the organism as a whole.This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin 4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.

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About the book

Full name Actin-Binding Proteins and Disease
Language English
Binding Book - Paperback
Date of issue 2010
Number of pages 348
EAN 9781441924537
ISBN 1441924531
Libristo code 01421251
Weight 587
Dimensions 155 x 235 x 20
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